Tenofovir disoproxil fumarate

ADVERTISEMENT

Identification

Molecular formula
C19H30N5O10P (Tenofovir disoproxil fumarate)
CAS Number
201341-05-1
IUPAC Name
[(2R,3S,5R)-5-(6-aminopurin-9-yl)-2-(phosphonooxymethyl)tetrahydrofuran-3-yl] [(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)tetrahydrofuran-2-yl]methyl hydrogen phosphate
Molecular Weight
635.52g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
2.2200g/cm3
Synonyms
26966-61-0
Interesting facts

Interesting Facts about the Compound

This complex compound, known for its intriguing structure and biological significance, has garnered attention in the fields of biochemistry and pharmaceuticals. Here are some fascinating insights:

  • Biological Relevance: The compound features components that resemble purine and pyrimidine bases, which are essential elements in the structure of nucleotides and nucleic acids. This gives the compound potential implications in genetic research and drug development.
  • Structure-Activity Relationship: The stereochemistry indicated by its detailed configuration presents opportunities to explore how different spatial arrangements can affect the compound's interactions with biological targets. Understanding this relationship is crucial for drug design.
  • Enzyme Inhibition: Due to its structural analogs to nucleotides, certain derivatives of this compound may act as inhibitors for specific enzymes involved in nucleotide metabolism. Research into these properties could contribute to the development of antiviral drugs.
  • Potential Antitumor Activity: Many compounds that share structural features with this one have demonstrated antitumor activity. Investigating its efficacy against cancer cells could reveal new therapeutic avenues.
  • Phosphorylation Potential: The presence of phosphonate groups suggests the compound may be a substrate for kinases, presenting a potential role in cellular signaling pathways. This aspect could position the compound as a valuable tool in studying molecular mechanisms.

In summary, this compound not only showcases the beauty of synthetic organic chemistry but also furthers our understanding of biological systems. As stated by a researcher in the field, "The complexity of such molecules is matched only by their potential for discovery." Thus, further exploration could lead to groundbreaking advances in biotechnology and medicine.

ADVERTISEMENT