Pemetrexed
- Molecular formula
- C20H21N5O6
- CAS Number
- 137281-23-3
- IUPAC Name
- (2S)-2-[[4-[(2,4-diaminoquinazolin-6-yl)methylamino]benzoyl]amino]butanedioic acid
- Molecular Weight
- 427.41g/mol
- Melting Point
- (Celsius)
- Boiling Point
- (Celsius)
- Density
- 1.6060g/cm3
- Synonyms
- Quinaspar
Identification
Interesting Facts About (2S)-2-[[4-[(2,4-diaminoquinazolin-6-yl)methylamino]benzoyl]amino]butanedioic acid
(2S)-2-[[4-[(2,4-diaminoquinazolin-6-yl)methylamino]benzoyl]amino]butanedioic acid is a fascinating compound often discussed in the fields of medicinal chemistry and pharmaceutical research. Its intricate structure is integral in the development of targeted therapies, particularly in the realm of cancer treatment. Here are some noteworthy points about this compound:
- Mechanistic Role: This compound functions as an important intermediate in the synthesis of various enzyme inhibitors that are crucial in anti-cancer drug development.
- Structural Features: The presence of a quinazoline ring and amino groups enhances its interaction with biological targets, allowing it to effectively bind to specific proteins involved in tumor growth.
- Targeted Therapy: Its design reflects a strategic approach in bioactive compound synthesis where precision is key, commonly used in the search for therapies that minimize side effects while maximizing therapeutic efficacy.
- Pharmaceutical Significance: As a member of a larger class of compounds, it shows promise in addressing resistance mechanisms often displayed by malignancies, thus paving the way for more effective cancer treatment protocols.
- Research Applications: This compound is frequently utilized in studies focusing on drug delivery systems, exploring its potential to improve therapeutic outcomes in various carcinomas.
Overall, the study of (2S)-2-[[4-[(2,4-diaminoquinazolin-6-yl)methylamino]benzoyl]amino]butanedioic acid embodies the complex interplay of chemical structure and biological function, showcasing the impact of organic chemistry in addressing some of the most pressing challenges in modern medicine.