Indomethacin

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Identification

Molecular formula
C19H16ClNO4
CAS Number
53-86-1
IUPAC Name
3-[[1-(1H-indol-3-ylmethyl)-2-oxo-2-(1-phenylethylamino)ethyl]carbamoyl]-5-methyl-hexanoic acid
Molecular Weight
357.80g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.3770g/cm3
Synonyms
3-({3-(1H-indol-3-yl)-1-oxo-1-[(1-phenylethyl)amino]propan-2-yl}carbamoyl)-5-methylhexanoic acid
Interesting facts

Interesting Facts about 3-[[1-(1H-indol-3-ylmethyl)-2-oxo-2-(1-phenylethylamino)ethyl]carbamoyl]-5-methyl-hexanoic acid

This complex compound is an intriguing example of how organic chemistry can combine various functional groups to create molecules with potential biological activity. Below are some noteworthy aspects of this fascinating compound:

  • Structural Diversity: The molecule integrates an indole ring, known for its presence in many natural products and pharmaceuticals, which may contribute to its biological properties.
  • Potential Therapeutic Applications: Compounds like this one are often investigated for their ability to modulate biological pathways, making them targets for drug development, especially in oncology and neurology.
  • Importance of Substituents: The presence of various functional groups, such as the carbamoyl and oxo groups, can significantly influence the compound's reactivity and interaction with biological targets, highlighting the importance of *structure-activity relationships (SAR)* in medicinal chemistry.
  • Synthetic Challenges: The synthesis of such a compound can be quite challenging due to its intricate structure, requiring multiple steps and precise conditions, which is both a testament to and a skill of the synthetic chemist.
  • Indole Moiety: This component not only enhances the compound's potential interaction with biological systems but also gives it interesting photophysical properties, making it applicable in various contexts, from drug design to organic electronics.

The exploration of compounds like 3-[[1-(1H-indol-3-ylmethyl)-2-oxo-2-(1-phenylethylamino)ethyl]carbamoyl]-5-methyl-hexanoic acid reflects the *endless possibilities* within organic chemistry and emphasizes the rich interconnection between molecular structure and function.

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