3-(2-chloro-1H-indol-3-yl)methylene)indolin-2-one

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Identification

Molecular formula
C17H11ClN2O
CAS Number
438-59-5
IUPAC Name
3-[(2-chloro-1H-indol-3-yl)methylene]indolin-2-one
Molecular Weight
312.77g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4167g/cm3
Synonyms
220749-41-7
Interesting facts

Interesting Facts about 3-[(2-chloro-1H-indol-3-yl)methylene]indolin-2-one

This unique compound, 3-[(2-chloro-1H-indol-3-yl)methylene]indolin-2-one, belongs to the family of indoline derivatives, which are well-regarded in medicinal chemistry for their broad spectrum of biological activities. Here are some intriguing aspects of this compound:

  • Biological Significance: Indole and indoline derivatives are often studied for their potential in pharmaceuticals. They exhibit various pharmacological activities, including antitumor, antidepressant, and anti-inflammatory effects.
  • Structure and Function: The compound features a complex structure that incorporates both chloro and methylene groups, positioning it favorably for interactions with biological pathways. The presence of chlorine is known to enhance certain properties, such as lipophilicity and binding affinity.
  • Research Potential: With the advancements in drug discovery, compounds like this one are often evaluated for their activity against various cancer cell lines. This opens up avenues for new treatments and therapeutic agents.
  • Synthetic Routes: The synthesis of indoline derivatives can involve unique strategies, often employing multi-step reactions that illustrate the complexity and creativity in modern organic synthesis.
  • Vibrant Interactions: The ability of this compound to participate in hydrogen bonding and π-π stacking interactions is crucial for its biological activity, making it a subject of interest for studies in molecular recognition.

In conclusion, the exploration of 3-[(2-chloro-1H-indol-3-yl)methylene]indolin-2-one represents a fascinating intersection of chemistry and pharmacology, where researchers are continually unveiling its potential benefits in treating various health conditions. As we advance our knowledge in this field, such compounds could pave the way for groundbreaking discoveries.

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