3-(2-Pyridylmethyl)-1H-indole

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Identification

Molecular formula
C14H12N2
CAS Number
15170-97-9
IUPAC Name
3-(2-pyridylmethyl)-1H-indole
Molecular Weight
220.27g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.2500g/cm3
Appearance
is otherwise consistent with many heterocyclic aromatic compounds, often presenting as a pale, off-white to light yellow solid when pure.
Synonyms
3-(2-Pyridylmethyl)indole
Interesting facts

Introducing 3-(2-pyridylmethyl)-1H-indole

3-(2-pyridylmethyl)-1H-indole is a fascinating compound that sits at the intersection of medicinal chemistry and organic synthesis. This compound is a derivative of indole, a structure known for its presence in many natural products and pharmaceuticals.

Key Features of 3-(2-pyridylmethyl)-1H-indole

  • Structural Significance: The indole structure is a bicyclic compound containing a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole ring. This unique architecture contributes to the compound's biological activity.
  • Pharmacological Potential: Compounds that contain both indole and pyridine rings often exhibit a range of biological activities, including anti-inflammatory, antidepressant, and antitumor properties. Research has indicated that indole derivatives play an integral role in drug design.
  • Research Applications: The incorporation of a pyridylmethyl group can enhance the interaction between the compound and various biological targets, making it a subject of interest in the fields of pharmaceutical chemistry and medicinal research.

Interesting Tidbits

Here are some additional aspects that make 3-(2-pyridylmethyl)-1H-indole noteworthy:

  • The indole ring alone is found in various neurotransmitters, including serotonin, highlighting the potential relevance of its derivatives in neurochemical research.
  • Due to its unique properties, 3-(2-pyridylmethyl)-1H-indole serves as a versatile intermediate in organic synthesis, paving the way for further derivatization and functionalization.
  • Researchers are increasingly focused on modifying this compound to explore how slight changes to its structure can impact its biological activity.

As a compound representing both complexity and therapeutic promise, 3-(2-pyridylmethyl)-1H-indole showcases the intricate relationship between structure and function in the realm of chemistry. Its study presents ongoing challenges and opportunities for chemists aiming to unlock new compounds for medicinal use.

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