Deferasirox

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Identification

Molecular formula
C21H15N3O4
CAS Number
201530-41-8
IUPAC Name
3-[3-(hydroxyamino)-3-oxo-prop-1-enyl]benzenecarbohydroxamic acid
Molecular Weight
373.37g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.6860g/cm3
Synonyms
N-Hydroxy-3-(3-(hydroxyamino)-3-oxoprop-1-en-1-yl)benzamide
Interesting facts

Interesting Facts about 3-[3-(hydroxyamino)-3-oxo-prop-1-enyl]benzenecarbohydroxamic acid

This compound, known as 3-[3-(hydroxyamino)-3-oxo-prop-1-enyl]benzenecarbohydroxamic acid, belongs to a fascinating class of organic compounds called hydroxamic acids. Hydroxamic acids are recognized for their broad range of biological and pharmaceutical applications. Here are some intriguing aspects about this particular compound:

  • Biological Relevance: Hydroxamic acids, including this compound, have shown potential as inhibitors for various enzymes, particularly metalloproteinases and histone deacetylases, which play critical roles in cancer progression and other diseases. This positions them as important candidates for drug development.
  • Structure and Function: The unique structure of this compound includes both a hydroxamic acid functional group and a hydroxyamino group, which could affect its reactivity and interactions with biological targets. The presence of the prop-1-enyl group suggests possible reactivity that may be vital in synthetically modifying the compound for enhanced bioactivity.
  • Research Potential: Scientists are actively exploring hydroxamic acids in the field of medicinal chemistry. This compound may serve as a lead for developing new therapeutics, emphasizing the importance of its structure in creating derivatives with improved efficacy.
  • Mechanism of Action: The proposed mechanisms by which hydroxamic acids exert their effects often relate to their ability to chelate metal ions. This chelation can inhibit enzyme activity and lead to significant biological outcomes, which are crucial in designing targeted therapies.
  • Pharmaceutical Applications: Due to their ability to interfere with key biological processes, derivatives of hydroxamic acids are being studied for their potential in treating various conditions, including cancer and inflammatory diseases.

In conclusion, 3-[3-(hydroxyamino)-3-oxo-prop-1-enyl]benzenecarbohydroxamic acid exemplifies the intriguing properties of hydroxamic acids, showcasing their potential in therapeutic applications and paving the way for future research. As more studies unfold, our understanding of such compounds may lead to groundbreaking advancements in medicinal chemistry.

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