Quetiapine

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Identification

Molecular formula
C21H25F2NO2S
CAS Number
111974-69-7
IUPAC Name
3-(3,8-difluoro-6H-benzo[c][1]benzothiepin-11-ylidene)-N,N-dimethyl-propan-1-amine
Molecular Weight
383.53g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4204g/cm3
Interesting facts

Interesting Facts about 3-(3,8-Difluoro-6H-Benzo[c][1]benzothiepin-11-ylidene)-N,N-Dimethyl-Propan-1-amine

This intriguing compound, with its complex structure and unique properties, has a variety of significant implications, especially in the field of medicinal chemistry. Below are some key insights about this compound:

  • Pharmaceutical Significance: Compounds that include a benzothiepin moiety are often explored for their potential therapeutic effects, particularly in neurological and psychiatric disorders. This particular compound's structure suggests it could play a role in drug development for conditions such as schizophrenia or depression.
  • Fluorination: The presence of fluorine atoms in its structure is notable. Fluorine is often incorporated into drug molecules to enhance their pharmacokinetic properties, improving absorption, distribution, and even metabolic stability. It also often leads to more potent compounds.
  • Synthesis Challenges: The synthesis of such a complex molecule is a subject of interest among organic chemists due to the need for precise control over reaction conditions to achieve the desired arrangement of atoms. Multistep synthetic routes with selective reactions can be quite challenging, making it a great subject for study in organic synthesis courses.
  • Potential Uses: Compounds like this one, characterized by the dimethylamine group, may exhibit interesting activities as modulators of neurotransmitter systems, which could lead to breakthroughs in understanding and treating mental health disorders.
  • Research Opportunities: The ongoing investigation into compounds with fused ring systems, such as this one, opens up various avenues for research, including structure-activity relationship (SAR) studies aimed at refining the efficacy and safety profiles of similar compounds.

In conclusion, 3-(3,8-Difluoro-6H-benzo[c][1]benzothiepin-11-ylidene)-N,N-dimethyl-propan-1-amine serves as an excellent example of how complex chemical structures can lead to functional versatility in drug development. This compound indeed inspires further investigation into its potential applications and properties.

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