PMSF (Phenylmethylsulfonyl fluoride)
- Molecular formula
- C7H7FO2S
- CAS Number
- 329-98-6
- IUPAC Name
- 3-[4-(benzenesulfonamido)phenyl]-2-methyl-prop-2-enehydroxamic acid
- Molecular Weight
- 174.21g/mol
- Melting Point
- (Celsius)
- Boiling Point
- (Celsius)
- Density
- 1.1240g/cm3
Identification
Interesting Facts about 3-[4-(Benzenesulfonamido)phenyl]-2-methyl-prop-2-enehydroxamic Acid
This compound, known for its unique structure and applications, is a member of the hydroxamic acid family. Hydroxamic acids have garnered interest in medicinal chemistry, particularly due to their ability to chelate metal ions and inhibit metal-dependent enzymes. Here are some compelling aspects of this compound:
- Versatile Applications: Hydroxamic acids are frequently studied for their potential roles in treating conditions such as cancer, cardiovascular diseases, and bacterial infections. The presence of the benzenesulfonamide group enhances its pharmacological profile.
- Enzyme Inhibition: This compound is particularly known for its ability to inhibit various metalloproteinases, which are critical in processes like tissue remodeling and cancer metastasis. Such attributes make it a subject of interest in cancer research.
- Metal Ion Interaction: The hydroxamic acid functional group is capable of forming stable complexes with transition metals such as zinc and iron, which plays a crucial role in its biological activity by interfering with metalloprotein functions.
- Soul of Sulfonamides: With the incorporation of the sulfonamide moiety, this compound benefits from enhanced water solubility and stability, making it potentially more effective as a pharmaceutical agent.
As with many synthetic compounds, the study of this hydroxamic acid provides valuable insights into the design of new drugs and therapeutic strategies. Scientists continue to explore its properties, aiming to unlock even more of its potential benefits in modern medicine.
In conclusion, the fascinating chemistry of 3-[4-(benzenesulfonamido)phenyl]-2-methyl-prop-2-enehydroxamic acid not only highlights the intricacies of molecular design but also showcases the intersections of chemistry and pharmacology, allowing researchers to delve deeper into the mechanisms of disease and treatment.