Loratadine

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Identification

Molecular formula
C22H23ClN2O
CAS Number
79794-75-5
IUPAC Name
3-(4-chlorophenyl)-1-[4-(2-hydroxypropyl)piperazin-1-yl]-3-phenyl-propan-1-one
Molecular Weight
382.89g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.2680g/cm3
Synonyms
beta-(p-Chlorophenyl)phenethyl 4-(2-hydroxypropyl)piperazinyl ketone
Interesting facts

Interesting Facts About 3-(4-Chlorophenyl)-1-[4-(2-Hydroxypropyl)piperazin-1-yl]-3-phenyl-propan-1-one

This compound, known for its complexity and intriguing structure, is a member of the propan-1-one family. Its design cleverly integrates multiple functional groups, rendering it a subject of interest in various fields of chemistry. Here are some key highlights about this fascinating compound:

  • Pharmacological Significance: This compound has been studied for its potential therapeutic effects, particularly in the realm of mental health, highlighting its utility in medicinal chemistry.
  • Structure Activity Relationship (SAR): The unique combination of a piperazine ring and a phenyl group contributes to its biological activity, providing insights into how different structural modifications can impact the efficacy of similar compounds.
  • Chlorinated Aromatics: The presence of a chlorophenyl moiety suggests interesting implications in reactivity and solubility, a common aspect of chlorinated compounds that can affect interactions with biological targets.
  • Hydroxypropyl Modification: The hydroxypropyl group can enhance solubility and biological activity, making this compound a subject of study for drug formulation and delivery systems.

As we delve deeper into its synthesis, reactivity, and biological applications, it becomes clear this compound offers a well-rounded example of how chemical modifications can lead to significant variations in properties and activities. Such compounds are a testament to the intricate design of nature at the molecular level, often leading to breakthroughs in pharmacology and therapeutic practices.

In summary, the multifaceted nature of 3-(4-Chlorophenyl)-1-[4-(2-Hydroxypropyl)piperazin-1-yl]-3-phenyl-propan-1-one serves as an excellent case study within the chemical community. Its exploration can yield valuable insights into drug development and the evolution of novel therapies.

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