Midazolam

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Identification

Molecular formula
C18H14ClFN3O3
CAS Number
59467-70-8
IUPAC Name
3-[7-chloro-5-(2-fluorophenyl)-2-oxo-4,5-dihydro-3H-1,4-benzodiazepin-4-ium-1-yl]propyl-diethyl-ammonium;dichloride
Molecular Weight
362.24g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.2000g/cm3
Synonyms
4084-17-7
Interesting facts

Interesting Facts About 3-[7-chloro-5-(2-fluorophenyl)-2-oxo-4,5-dihydro-3H-1,4-benzodiazepin-4-ium-1-yl]propyl-diethyl-ammonium;dichloride

This compound is a remarkable example of a modified benzodiazepine, notable for its intricate structure and potential pharmacological applications. As part of the benzodiazepine class, it exhibits distinct properties that can significantly influence its interaction with biological systems.

Key Features

  • Pharmacological Relevance: Benzodiazepines are well-known for their anxiolytic, sedative, and muscle relaxant properties. This compound’s unique modifications may enhance its affinity for specific receptors.
  • Chlorine and Fluorine Substituents: The presence of chlorine and fluorine atoms often leads to increased lipophilicity, potentially improving the compound's ability to cross the blood-brain barrier. This could significantly affect its efficacy and side-effects.
  • Ammonium Salt Form: The dichloride form indicates the compound is a quaternary ammonium salt, which can impart solubility benefits and modify how the compound interacts with the body compared to uncharged counterparts.
  • Structural Insights: With its dihydro-benzodiazepine core, this compound underscores how structural variations among compounds in the same class can impart unique biological activities.

Interesting Applications

This compound, like other benzodiazepines, holds promise for various therapeutic applications:

  • Treatment of anxiety disorders
  • Potential role in managing sleep disturbances
  • Exploration for neuroprotective effects

In conclusion, the complex architecture and functional modifications of 3-[7-chloro-5-(2-fluorophenyl)-2-oxo-4,5-dihydro-3H-1,4-benzodiazepin-4-ium-1-yl]propyl-diethyl-ammonium;dichloride present a fascinating case study. As researchers delve deeper into its characteristics, this compound may reveal even more about the intricate relationship between molecular structure and biological function.

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