Cefotaxime

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Identification

Molecular formula
C16H17N5O7S2
CAS Number
64485-93-4
IUPAC Name
3-(acetoxymethyl)-7-[[2-(diethylcarbamoylsulfanyl)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Molecular Weight
455.47g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4266g/cm3
Synonyms
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[[[(diethylamino)carbonyl]thio]acetyl]amino]-8-oxo-
Interesting facts

Interesting Facts about 3-(acetoxymethyl)-7-[[2-(diethylcarbamoylsulfanyl)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

This compound, often recognized for its complex structure, is a member of the class of antibiotics known as thiazolidinones. These compounds exhibit a variety of biological activities that pique scientific interest.

Biological Significance

3-(acetoxymethyl)-7-[[2-(diethylcarbamoylsulfanyl)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid has garnered attention due to its therapeutic potential. Key attributes include:

  • Antimicrobial Activity: The compound displays potent activity against a range of bacterial strains, which makes it a candidate for developing new antibiotics.
  • Mechanism of Action: Its unique structural features may facilitate innovative mechanisms of action, allowing it to overcome bacterial resistance.
  • Synergistic Effects: Research indicates that when combined with other agents, it may enhance the efficacy of existing treatments.

Chemical Structure Insights

The bicyclic structure of this compound is particularly fascinating. It allows for spatial conformations that impact interactions with biological targets. Some insights include:

  • Thiazolidinone Ring: Residing in the core of the molecule, it contributes to its antimicrobial properties.
  • Functional Groups: The presence of an acetoxymethyl group and carbamoylsulfanyl moiety enhances solubility and stability, which is crucial for its medicinal applications.

In summary, this compound represents an exciting frontier in medicinal chemistry, providing a platform for further research and potential therapeutic applications. As scientists continue to explore its properties, we may unlock new avenues for combating bacterial infections in an era of increasing antibiotic resistance.

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