Varenicline

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Identification

Molecular formula
C13H13N3O
CAS Number
249296-44-4
IUPAC Name
3-(azetidin-2-ylmethoxy)pyridine
Molecular Weight
211.27g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.2000g/cm3
Synonyms
CHEMBL190589
Interesting facts

Interesting Facts about 3-(azetidin-2-ylmethoxy)pyridine

3-(azetidin-2-ylmethoxy)pyridine is a fascinating compound with diverse applications in medicinal chemistry and organic synthesis. Below are some intriguing aspects of this compound:

  • Structural Significance: This compound contains both a pyridine ring and an azetidine moiety. The combination of these structures allows for unique interactions with various biological targets, making it an excellent candidate for drug development.
  • Biological Activity: Molecules that include pyridine rings are known for their prevalence in natural products and as pharmacophores. The azetidine component has been associated with enhancing the activity of pharmaceutical agents.
  • Synthetic Utility: The methoxy group plays a crucial role in modulating the lipophilicity of the compound, impacting its pharmacokinetic properties. This feature is highly desirable when designing new therapeutic agents.
  • Research Focus: Compounds like 3-(azetidin-2-ylmethoxy)pyridine are often studied for their potential antitumor and antibacterial properties. Researchers are keen on understanding how variations in structure can alter efficacy and selectivity in biological systems.
  • Applications in Drug Design: The strategic incorporation of different substituents on the pyridine and azetidine rings can lead to a library of related compounds, facilitating the optimization of pharmacological properties through structure-activity relationship (SAR) studies.

In summary, 3-(azetidin-2-ylmethoxy)pyridine represents a fascinating area of study within the realm of organic and medicinal chemistry. Its unique structure, potential biological activity, and role in drug discovery underscore its importance in current research. As quoted by a notable chemist, "The beauty of medicinal chemistry lies in the intricate dance between structure and function."

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