Hydrochlorothiazide

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Identification

Molecular formula
C7H8ClF3N3O4S2
CAS Number
58-93-5
IUPAC Name
3-benzyl-1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide
Molecular Weight
297.74g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.7173g/cm3
Appearance
that is typical for many pharmaceutical compounds.
Synonyms
BENDROFLUMETHIAZIDE
Interesting facts

Interesting Facts about 3-benzyl-1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide

This intriguing compound, known for its complex structure, is a member of the benzothiadiazine class, which has garnered interest in medicinal chemistry. Here are some compelling insights about this unique chemical:

  • Pharmaceutical Potential: Compounds within the benzothiadiazine family are often studied for their pharmacological properties, particularly in the context of antihypertensive and diuretic medications.
  • Trifluoromethyl Group: The presence of the trifluoromethyl group (–CF3) enhances the compound's stability and lipophilicity, which helps in modulating its biological activity and bioavailability.
  • Thiadiazine Framework: The thiadiazine ring offers unique electronic properties that can influence reactivity and interactions with biological targets, making such compounds attractive for drug discovery.
  • Environmental Impact: This compound also reflects ongoing discussions regarding environmental sustainability, emphasizing the need for understanding the behavior of fluorinated compounds in ecosystems.
  • Diversity of Derivatives: The ability to modify the subtype groups on the benzothiadiazine core leads to a vast array of derivatives with varying properties, highlighting the versatility of synthetic chemistry in exploring diverse chemical spaces.

In conclusion, 3-benzyl-1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide represents a fascinating intersection of organic chemistry and medicinal applications. Its unique properties and potential applications make it a subject of ongoing research and exploration in the chemical sciences.

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