3-Hydroxy-3-(2-pyridylmethyl)indolin-2-one

Molecular formula: C₁₄H₁₂N₂O₂
CAS Number: null
IUPAC Name: 3-hydroxy-3-(2-pyridylmethyl)indolin-2-one
Molecular Weight: 252.27g/mol
Melting Point: (Celsius)
Boiling Point: (Celsius)
Density: 1.3213g/cm3
Synonyms: ALPHA-(3-HYDROXY-2-OXO-3-INDOLINYL)-2-METHYLPYRIDINE

Interesting facts

Interesting Facts about 3-hydroxy-3-(2-pyridylmethyl)indolin-2-one

The compound 3-hydroxy-3-(2-pyridylmethyl)indolin-2-one, often abbreviated to its more manageable core structure, has garnered significant interest in the field of medicinal chemistry.

Unique Structural Features

Indole Framework: The presence of the indolin-2-one core provides a foundation that enhances biological activity.
Pyridine Interaction: The 2-pyridylmethyl group plays a crucial role in receptor binding, making this compound a candidate for drug design.
Hydroxyl Group: The hydroxy functionality can participate in hydrogen bonding, influencing solubility and interaction with biological targets.

Biological Activities

This compound has been studied for various potential biological activities, particularly:

Anticancer Properties: Preliminary studies suggest it may exhibit activity against certain cancer cell lines.
Antimicrobial Effects: Research indicates potential efficacy in inhibiting the growth of specific microbial strains.
Neuroprotective Potential: There is promise in exploring its effects on neurodegenerative diseases.

Applications in Drug Design

Given its unique molecular structure, 3-hydroxy-3-(2-pyridylmethyl)indolin-2-one serves as an interesting scaffold for further modifications aimed at improving pharmacological properties. The flexibility in the indolin-2-one structure makes it a suitable candidate for:

Designing novel therapeutic agents
Developing selective kinase inhibitors
Creating compounds targeting specific biological pathways

Research and Future Directions

Continued research into 3-hydroxy-3-(2-pyridylmethyl)indolin-2-one will likely unveil further applications and enhance our understanding of its mechanisms of action. As the need for innovative drug solutions grows, compounds such as this could be pivotal in overcoming current medical challenges.