Metronidazole

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Identification

Molecular formula
C4H6N4O2
CAS Number
443-48-1
IUPAC Name
3-methyl-5-nitro-imidazol-4-amine
Molecular Weight
145.11g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4545g/cm3
Synonyms
4531-54-8
Interesting facts

Interesting Facts About 3-Methyl-5-Nitro-Imidazol-4-Amine

3-Methyl-5-nitro-imidazol-4-amine is a fascinating compound with significant implications in various fields, especially in medicinal chemistry. Below are some notable facts:

  • Pharmaceutical Potential: This compound serves as a precursor in the synthesis of various pharmaceuticals, notably as an intermediate in the development of anti-parasitic and anti-fungal agents.
  • Imidazole Ring: The imidazole group is a five-membered heterocyclic ring that plays a crucial role in the biological activity of many biomolecules. It’s found in important compounds such as histidine, a vital amino acid.
  • Nitro Group Reactivity: The nitro group in this compound gives it unique chemical properties, making it a target for reduction reactions. This can lead to the formation of amines, which are often more biologically active.
  • Research Interest: The nitro-imidazole derivatives have been the subject of numerous studies due to their effectiveness against parasites and their potential role in hypoxic cell sensitization in cancer therapy.
  • Environmental Insight: Interesting to note, compounds similar to 3-methyl-5-nitro-imidazol-4-amine can be found in some environmental studies, particularly regarding soil and water contaminants due to their synthetic production.

In summary, 3-methyl-5-nitro-imidazol-4-amine not only provides insights into pharmaceutical development but also underscores the importance of chemical reactivity and biological applications. The ongoing research around this compound continues to pave the way for innovative therapeutic strategies.

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