3-Methylquinazolin-4-one

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Identification

Molecular formula
C9H8N2O
CAS Number
17609-86-6
IUPAC Name
3-methylquinazolin-4-one
Molecular Weight
160.18g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.2103g/cm3
Synonyms
4(3H)-QUINAZOLINONE, 3-METHYL-
Interesting facts

Interesting Facts about 3-Methylquinazolin-4-one

3-Methylquinazolin-4-one is a fascinating compound that belongs to the quinazolinone family, a group known for their diverse biological activities. Here are some captivating insights into this intriguing molecule:

  • Medicinal Potential: Many derivatives of quinazolinones, including 3-methylquinazolin-4-one, have shown significant promise in medicinal chemistry, particularly as antitumor agents and antimicrobial substances.
  • Biological Activity: Research has indicated that compounds within this class can exhibit various biological properties, such as anti-inflammatory and antiviral activities, making them interesting candidates for drug development.
  • Versatile Synthesis: The synthesis of 3-methylquinazolin-4-one can be accomplished through various methods, including cyclization reactions, which can lead to the exploration of many synthetic pathways and enhance understanding of reaction mechanisms.
  • Pharmacophoric Features: The quinazolinone structure contains key pharmacophoric components, such as the carbonyl and nitrogen atoms, which can interact with biological targets, making them crucial in lead optimization for drug candidates.
  • Role in Research: Ongoing studies often explore modifications of the basic structure to improve efficacy and reduce toxicity, emphasizing the importance of structure-activity relationships (SAR) in pharmaceutical research.

In summary, 3-methylquinazolin-4-one stands out not only for its unique structure but also for its potential applications in fields ranging from medicinal chemistry to pharmacology. As research progresses, this compound could play an integral role in the development of new therapeutic agents that could benefit human health.

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