(3-nitrophenyl)boronic acid

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Identification

Molecular formula
C6H6BNO4
CAS Number
133730-24-8
IUPAC Name
(3-nitrophenyl)boronic acid
Molecular Weight
168.96g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4680g/cm3
Synonyms
3-nitrophenylboronic acid
Interesting facts

Interesting Facts about (3-Nitrophenyl)boronic Acid

(3-Nitrophenyl)boronic acid is a fascinating compound that plays a critical role in various fields of chemistry, especially in organic synthesis and medicinal chemistry. Here are some noteworthy aspects:

  • Building Block in Organic Synthesis: This compound serves as a versatile building block for synthesizing more complex molecular structures, particularly in the field of drug discovery. Its boronic acid functionality allows for the formation of stable boronate esters, facilitating further chemical transformations.
  • Applications in Biomaterials: (3-Nitrophenyl)boronic acid is utilized in the development of bioresponsive materials. For instance, it can be part of drug delivery systems that respond to specific biological triggers, showcasing its importance in targeted therapy.
  • Covalent Labeling: Its reactivity with diols allows (3-nitrophenyl)boronic acid to be employed in covalent labeling techniques, which are essential for studying biological interactions. This enables researchers to investigate molecular pathways and interactions in living organisms.
  • Role in Diagnostics: The compound can also be part of optical sensing systems. The unique properties of the nitrophenyl group make it useful for developing sensors that detect specific biomolecules, enhancing diagnostic capabilities.
  • Research Applications: Due to its multi-functionality, (3-nitrophenyl)boronic acid is often used in academic research to explore new synthetic routes and mechanisms, providing valuable insights into chemical behavior and interaction.

As one scientist noted, “The integration of boronic acids in synthetic methodology has revolutionized the approaches we take in organic synthesis.” The properties of (3-nitrophenyl)boronic acid exemplify this revolution, making it a compound of great interest in both research and practical applications.

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