Firocoxib

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Identification

Molecular formula
C17H15NO4S
CAS Number
189954-96-9
IUPAC Name
3-phenyl-2-[(4-phenylphenyl)sulfonylamino]propanoic acid
Molecular Weight
336.39g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.3500g/cm3
Synonyms
MMP-2/MMP-9InhibitorI
Interesting facts

Interesting Facts about 3-phenyl-2-[(4-phenylphenyl)sulfonylamino]propanoic acid

This compound, often abbreviated as 3-phenyl sulfonamide, is a fascinating example of organic chemistry's ability to create versatile drugs. Here are some captivating aspects:

  • Pharmacological Potential: Compounds like 3-phenyl sulfonamide have shown promise in medicinal chemistry, particularly in the development of anti-inflammatory and analgesic medications. This highlights the importance of sulfonamide structures in pharmacology.
  • Synthetic Route: The synthesis of this compound often involves key reactions such as nucleophilic substitution and acylation. Understanding these reactions gives students a profound insight into synthetic organic chemistry techniques.
  • Diverse Applications: Beyond medicinal uses, compounds containing sulfonamide groups are known to exhibit properties in various fields, including agriculture and materials science, showcasing the multifaceted nature of this chemical class.
  • Structure-Activity Relationship: The presence of both phenyl and sulfonyl groups in this compound allows scientists to explore the interplay between structure and activity, enhancing the understanding of how molecular design influences biological behavior.
  • Historical Significance: Sulfonamides, as a class, were among the first antimicrobial agents discovered, leading the way to antibiotics and significantly shaping modern medicine.

In summary, 3-phenyl-2-[(4-phenylphenyl)sulfonylamino]propanoic acid is not just a compound of interest due to its structure, but also plays a crucial role in advancing our understanding of drug development and therapeutic applications. As one researcher aptly stated, "The beauty of organic compounds lies in their ability to adapt and serve myriad functions in both nature and industry."

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