3-(Pyrrolidin-1-ylmethyl)-1H-indole

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Identification

Molecular formula
C13H16N2
CAS Number
5118-13-8
IUPAC Name
3-(pyrrolidin-1-ylmethyl)-1H-indole
Molecular Weight
198.29g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.1526g/cm3
Synonyms
5379-94-2
Interesting facts

Interesting Facts about 3-(pyrrolidin-1-ylmethyl)-1H-indole

3-(pyrrolidin-1-ylmethyl)-1H-indole is a fascinating compound with unique structural features and diverse applications in medicinal chemistry. Here are some key points that highlight its significance:

  • Structural Biochemistry: This compound contains both an indole ring and a pyrrolidine moiety. The indole structure is prevalent in various natural alkaloids and plays a crucial role in numerous biochemical processes, including neurotransmission.

  • Biological Activity: Compounds containing the indole ring are often found in medicinal agents. Research suggests that 3-(pyrrolidin-1-ylmethyl)-1H-indole may exhibit properties related to neuroactivity, making it a potential candidate for further pharmacological studies.

  • Cheminformatics: The unique 3D conformation of 3-(pyrrolidin-1-ylmethyl)-1H-indole allows researchers to explore its interaction with various biological targets. This characteristic makes it a valuable tool for drug design and discovery.

  • Research Implications: The structural and functional complexity raises interesting questions for scientists. As one researcher noted, “The ability to modify the pyrrolidine group opens avenues for creating derivatives with enhanced biological profiles.”

  • Synthesis Insights: The synthesis of this compound can involve various methods, including those employing novel coupling reactions. This provides students with practical experience in synthetic organic chemistry techniques.

In summary, 3-(pyrrolidin-1-ylmethyl)-1H-indole is not just a chemical entity; it represents a rich area of exploration within the realms of pharmacology, organic synthesis, and molecular design. Its integration into research can lead to significant advancements in the understanding of drug mechanisms and the development of therapeutic agents.

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