Estradiol

ADVERTISEMENT

Identification

Molecular formula
C18H24O2
CAS Number
50-28-2
IUPAC Name
(3R,5S,17S)-3-methoxy-10,13,17-trimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-ol
Molecular Weight
272.38g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.1260g/cm3
Interesting facts

Interesting Facts about (3R,5S,17S)-3-methoxy-10,13,17-trimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-ol

This compound is a fascinating member of the steroid family, known for its complex structure and significant biological activity. Here are some noteworthy aspects that make it particularly interesting:

  • Structural Complexity: The numerous methyl groups and unique stereochemistry contribute to its intricate three-dimensional shape, which is vital for its interactions and functions in biological systems.
  • Natural Occurrence: Compounds similar to this have been isolated from various natural sources, particularly in medicinal plants, highlighting their potential roles in traditional medicine.
  • Biological Significance: Many steroids, including those related to this compound, play critical roles in regulating physiological processes like metabolism, immune response, and sexual development.
  • Potential Pharmacological Applications: Research into compounds with similar structures may lead to the development of new therapeutic agents, particularly in the fields of endocrinology and oncology.
  • Stereochemical Precision: The designation of stereocenters (3R, 5S, 17S) is crucial as even minor changes in stereochemistry can lead to significant alterations in biological activity.

In conclusion, (3R,5S,17S)-3-methoxy-10,13,17-trimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-ol is not just a chemical compound but a key piece in the puzzle of biochemistry that bridges structural chemistry and biological function. Studying such compounds opens avenues for greater understanding and innovation in pharmaceutical sciences.

ADVERTISEMENT