Estradiol

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Identification

Molecular formula
C18H24N2
CAS Number
50-28-2
IUPAC Name
(3S,8R,9S,10R,13S,14S,17S)-N3,10,13-trimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,17-diamine
Molecular Weight
272.38g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.2300g/cm3
Synonyms
Androst-5-ene-3, 17-diamine, N3-methyl-, (3.beta., 17.beta.)-
Interesting facts

Interesting Facts about (3S,8R,9S,10R,13S,14S,17S)-N3,10,13-trimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,17-diamine

This complex compound showcases a fascinating structure known for its unique stereochemistry and potential applications in medicinal chemistry. Here are some intriguing points to consider:

  • Stereochemical Complexity: The compound exhibits multiple stereocenters, highlighting the significance of chirality in biological systems. Chirality can influence how molecules interact with biological receptors, making it a critical factor in drug design.
  • Potential Medicinal Applications: Due to its unique bicyclic structure, this compound could be explored for its potential therapeutic properties. Compounds with similar skeletons have shown promise in treating various conditions, particularly in the realm of cancer therapy and hormonal regulation.
  • Synthetic Challenges: The synthesis of such a highly substituted compound presents substantial challenges in organic chemistry, particularly in achieving the desired stereochemistry. Chemists often utilize advanced techniques like asymmetric synthesis and chiral catalysts to navigate these obstacles.
  • Structural Inspiration: The structural motifs found in this compound resemble those present in naturally occurring steroids and alkaloids, which often exhibit significant biological activity. Understanding these motifs can inspire the development of new drugs.
  • Research Utility: This compound may serve as a valuable tool in research laboratories for studying the effects of structural modifications on biological activity, contributing to a deeper understanding of structure-activity relationships (SAR).

As we continue to delve into the world of complex organic compounds like this one, we gain insights not only into their intricate structures but also into their potential to revolutionize medicine and enhance our understanding of chemical reactivity.

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