Tenofovir alafenamide
- Molecular formula
- C21H29N3O9P
- CAS Number
- 379270-37-8
- IUPAC Name
- 4-[2-[2-[3-acetamido-2-[[[5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-5-hydroxy-6-(hydroxymethyl)tetrahydropyran-4-yl]oxypropanoylamino]propanoylamino]-5-[[5-amino-1-[[2-(1-carboxyethylamino)-1-methyl-2-oxo-ethyl]carbamoyl]pentyl]amino]-5-oxo-pentanoic acid
- Molecular Weight
- 476.48g/mol
- Melting Point
- (Celsius)
- Boiling Point
- (Celsius)
- Density
- 1.6801g/cm3
- Synonyms
- GTPL1291
Identification
Interesting Facts about 4-[2-[2-[3-Acetamido-2-[[[5-(2,4-Dioxopyrimidin-1-yl)-3,4-Dihydroxy-Tetrahydrofuran-2-yl]Methoxy-Hydroxy-Phosphoryl]Oxy-Hydroxy-Phosphoryl]Oxy-5-Hydroxy-6-(Hydroxymethyl)Tetrahydropyran-4-yl]Oxypropanoylamino]Propanoylamino]-5-[[5-Amino-1-[[2-(1-Carboxyethylamino)-1-Methyl-2-Oxo-Ethyl]Carbamoyl]Pentyl]Amino]-5-Oxo-Pentanoic Acid
This complex compound is a *bioactive molecule* that resides at the intersection of medicinal chemistry and pharmacology. Its structure reveals multiple functional groups, which play crucial roles in its biological activity. Here are several fascinating points about this compound:
- Multifunctionality: The diverse functional groups present in the structure highlight the compound's multifaceted nature, allowing for potential interactions with various biological systems.
- Phosphorylation: The presence of phosphoryl groups suggests that this compound may engage in phosphorylation reactions, making it a target for research into signal transduction and enzyme regulation.
- Intermolecular Interactions: Its intricate design enables the possibility of forming strong intermolecular interactions, which can enhance its efficacy as a drug candidate.
- Medicinal Potential: The derivation from purines and pyrimidines points to potential application in treating conditions like cancer or infections, making it an exciting subject for further investigation.
- Structure-Activity Relationship: Understanding how modifications to its structure affect biological activity could reveal valuable insights into drug design and development.
In exploring this compound, researchers are not just analyzing a potential pharmacological agent; they are delving into the *complex interplay of chemistry and biology*. As scientists say, "The great thing about science is that it’s true whether or not you believe in it," and this compound exemplifies the profound impact that chemical structures can have on health and medicine.
Ultimately, the journey of studying such chemical constituents is both challenging and rewarding, offering new pathways to innovative therapies and a deeper understanding of life at the molecular level.