Methotrexate

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Identification

Molecular formula
C20H22N8O5
CAS Number
59-05-2
IUPAC Name
4-[(2-amino-4-oxo-1H-pteridin-6-yl)methyl-methyl-amino]benzoic acid
Molecular Weight
454.43g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.0000g/cm3
Interesting facts

Interesting Facts about 4-[(2-amino-4-oxo-1H-pteridin-6-yl)methyl-methyl-amino]benzoic acid

This fascinating compound—known for its structural complexity and biochemical significance—belongs to a category of organic compounds often used in pharmaceutical research and development. Below are some compelling insights regarding this intriguing molecule:

  • Biological Importance: This compound features a pteridine ring structure, which is pivotal in the metabolism of folate and nucleic acids in biological systems.
  • Pharmaceutical Applications: Analogues of this compound have shown activity against various diseases, particularly some cancers, through inhibition of specific enzyme pathways.
  • Structure-Activity Relationship: The structural components of this compound allow for a diverse range of modifications, leading to a broad spectrum of potential biological activities, which are of great interest in medicinal chemistry.
  • Interactions: Researchers are studying its interactions with target proteins to uncover mechanisms of action and potential therapeutic uses.
  • Research Significance: The complexity of its structure provides valuable insights into synthetic strategies, yielding information that can enhance the design of novel pharmaceuticals.

As you can see, 4-[(2-amino-4-oxo-1H-pteridin-6-yl)methyl-methyl-amino]benzoic acid represents a bridge between chemistry and biology, embodying the richness of structural chemistry while offering hope in therapeutic applications. As Nobel laureate Ahmed Zewail once said, "The true chemistry lies in the interactions and transformations." This compound is a testament to that ideology!

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