Indoline-2-one derivative

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Identification

Molecular formula
C17H26N2O
CAS Number
2217-46-7
IUPAC Name
4-[2-(dipropylamino)ethyl]indolin-2-one
Molecular Weight
288.43g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.1537g/cm3
Synonyms
ropinirole
Interesting facts

Interesting Facts about 4-[2-(dipropylamino)ethyl]indolin-2-one

The compound 4-[2-(dipropylamino)ethyl]indolin-2-one belongs to the class of indolinones, which are important in various fields of research and applications. Here are some fascinating insights into this compound:

  • Structural Significance: The indolinone structure is renowned for its versatile chemical properties and biological activities. The functional groups attached to the indole ring can significantly influence its reactivity.
  • Biological Activity: Compounds with indolinone structures have been investigated for their potential in medicinal chemistry, particularly as antidepressants, antipsychotics, and even as anti-cancer agents.
  • Role of Alkyl Amines: The dipropylamino group in this compound might enhance its lipophilicity and possibly lead to increased efficacy in biological systems by improving membrane penetration.
  • Research Applications: Scientists often explore compounds like this for drug design. The ability to modify the amino chain could lead to derivatives that target specific receptors in the body.
  • Synthetic Interest: The synthesis of compounds with indolinone frameworks often involves several interesting reactions, including cyclization and aromatic substitutions, showcasing the creativity of chemists.

A quote from renowned organic chemist Janet I. Van Horne emphasizes the significance of such compounds: "The diversity of indole derivatives in nature is a treasure trove for medicinal chemistry." This underlines the importance of 4-[2-(dipropylamino)ethyl]indolin-2-one as a potential lead compound in drug discovery.


In summary, the exploration of 4-[2-(dipropylamino)ethyl]indolin-2-one represents a blend of synthetic creativity and biological potential, making it an intriguing subject of study in modern chemistry.

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