Tenofovir disoproxil fumarate

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Identification

Molecular formula
C19H30N5O10P
CAS Number
202138-50-9
IUPAC Name
4-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]-2-fluoro-butanoic acid
Molecular Weight
519.40g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4900g/cm3
Synonyms
PD041963
Interesting facts

Interesting Facts About 4-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]-2-fluoro-butanoic acid

This compound is a fascinating example of a complex molecule that highlights the intricate relationships between structure and function in medicinal chemistry. Here are some intriguing points about this compound:

  • Structure Complexity: The compound showcases various functional groups, including amino, hydroxyl, and phosphonooxy groups, which play critical roles in biological interactions. This complexity contributes to its potential efficacy as a therapeutic agent.
  • Biological Significance: Compounds like this often interact with biological macromolecules, such as proteins and nucleic acids, potentially acting as inhibitors or modulators within cellular pathways.
  • Research and Development: The synthesis of this compound may involve advanced synthetic methodologies, which is a testament to the evolving nature of organic chemistry and drug design.
  • Potential Applications: Given its unique structure, this compound could hold promise in treating various diseases, possibly in the realm of cancer treatment or antiviral therapies through the inhibition of specific biological targets.
  • Phosphorylation Impact: The presence of multiple phosphoryl groups suggests that this compound could influence metabolic pathways and play a role in signal transduction, a crucial aspect in the development of pharmacological agents.

In conclusion, the complexity and potential applications of 4-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]-2-fluoro-butanoic acid illustrate the dynamic and ever-evolving field of chemistry, where each new compound can open the door to exciting scientific discoveries.

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