Tenofovir disoproxil fumarate
- Molecular formula
- C19H30N5O10P
- CAS Number
- 202138-50-9
- IUPAC Name
- 4-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]butanoic acid
- Molecular Weight
- 635.51g/mol
- Melting Point
- (Celsius)
- Boiling Point
- (Celsius)
- Density
- 1.4900g/cm3
- Synonyms
- CMX
Identification
Interesting Facts about 4-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]butanoic acid
This compound is a fascinating example of the complexity and functionality inherent in biochemical molecules, particularly in the context of nucleotide analogs and their applications in medicinal chemistry.
Key Features:
- Structure Complexity: The structure of this compound includes multiple functional groups that suggest a rich potential for interaction with biological targets.
- Amino Group Influence: The presence of the 6-aminopurine component highlights its potential role in mimicking nucleobases, enhancing its relevance to nucleic acid behavior.
- Phosphorylation Sites: The multiple phosphoryl groups in its structure are indicative of energy transfer and signaling roles, which are crucial in various biochemical pathways.
- Applications: This compound may serve as an important model for studying phosphorylated nucleosides, which are significant in cellular processes such as protein synthesis, cell signaling, and energy metabolism.
Research and Medicinal Implications:
Due to its intricate design, the compound can be a candidate for drug development, particularly in targeting specific enzymes or receptors in cellular pathways. Scientists might explore its potential as:
- Inhibitors or enhancers of nucleic acid synthesis.
- Therapeutic agents for conditions like cancer or viral infections, where nucleotide metabolism plays a key role.
In conclusion, 4-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]butanoic acid demonstrates the intricate balance of structure and function that characterizes many important biochemical compounds. It's a prime example of how chemical complexity can lead to significant biological activity.