Tenofovir disoproxil fumarate

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Identification

Molecular formula
C19H30N5O10P
CAS Number
201341-05-1
IUPAC Name
[[4-[[3-[(4-amino-3-fluoro-4-oxo-butyl)amino]-3-oxo-propyl]amino]-3-hydroxy-2,2-dimethyl-4-oxo-butoxy]-hydroxy-phosphoryl] [5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methyl hydrogen phosphate
Molecular Weight
519.40g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4000g/cm3
Interesting facts

Exploring a Complicated Compound

The compound named 4-[[3-[(4-amino-3-fluoro-4-oxo-butyl)amino]-3-oxo-propyl]amino]-3-hydroxy-2,2-dimethyl-4-oxo-butoxy]-hydroxy-phosphoryl] [5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methyl hydrogen phosphate holds significant interest for scientists due to its intricate structure and potential biological applications. Here are some intriguing aspects of this compound:

  • Complex Pharmacophore: The compound showcases a complex pharmacophore that could interact with various biological targets, making it a candidate for drug discovery.
  • Fluoro-Modification: The presence of a fluorine atom is notable as it can enhance metabolic stability, thereby improving the compound's efficacy and bioavailability.
  • Phosphorylation: The phosphoryl group incorporated in its structure may confer essential characteristics for biological activity, particularly in medicinal chemistry.
  • Potential Applications: Its structural components suggest it could possess properties useful in treatments for conditions like cancer or bacterial infections, meriting further investigation.
  • Interdisciplinary Appeal: This compound represents an intersection of organic chemistry, medicinal chemistry, and biochemistry, appealing to a wide range of research fields.

"Understanding such complex molecules is vital for advancing pharmaceutical innovation." This compound exemplifies the intricate relationship between structure and function in drug development and highlights the importance of synthetic organic chemistry in creating novel therapeutic agents. As research progresses, compounds like this may pave the way for breakthroughs in targeted therapies and personalized medicine.

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