Rosuvastatin

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Identification

Molecular formula
C22H28FN3O6
CAS Number
147098-20-2
IUPAC Name
4-[(3R,5S)-3-hydroxy-10,13-dimethyl-7-oxo-1,2,3,4,5,6,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid
Molecular Weight
481.54g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.2870g/cm3
Appearance
in pharmaceutical forms can vary but generally consists of small, round, and coated tablets.
Interesting facts

Interesting Facts about 4-[(3R,5S)-3-hydroxy-10,13-dimethyl-7-oxo-1,2,3,4,5,6,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid

This compound, often associated with complex biochemical processes and pharmacological applications, has several intriguing aspects that make it a topic of interest in the field of chemistry.

Structural Significance

  • Stability and Conformation: The intricate structure of this compound, with multiple stereocenters, contributes to its stability and unique conformational possibilities.
  • Functional Groups: The presence of hydroxyl (-OH) and carbonyl (=O) functional groups plays a crucial role in its reactivity and interactions with biological systems.

Biological Implications

  • Potential Therapeutic Uses: Compounds similar to this one have been explored for their pharmaceutical properties, particularly in areas such as anti-inflammatory or anti-cancer treatments.
  • Steroid-Like Activity: Given its structural similarities to steroidal compounds, it may exhibit hormonal functions or modulate biochemical pathways.

Challenges in Synthesis

Synthesizing a molecule of such complexity presents a significant challenge for chemists. The multifaceted stereochemistry requires:

  • Selective Reactions: Careful selection of reagents and conditions to achieve desired stereochemical outcomes.
  • Purification Techniques: Advanced methods to isolate and purify the compound from reaction mixtures, ensuring high yields of the target molecule.

Conclusion

In summary, 4-[(3R,5S)-3-hydroxy-10,13-dimethyl-7-oxo-1,2,3,4,5,6,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid is a fascinating compound that exemplifies the complex relationship between chemical structure and biological function. Its study not only enhances our understanding of natural products but also paves the way for future innovations in medicinal chemistry.

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