Meclizine dihydrochloride

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Identification

Molecular formula
C24H32Cl2N2O3
CAS Number
3185-12-2
IUPAC Name
4-[4-(2-methoxyphenyl)piperazin-1-yl]-1-(3,4,5-trimethoxyphenyl)butan-1-ol;dihydrochloride
Molecular Weight
482.44g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.3500g/cm3
Synonyms
16785-29-8
Interesting facts

Interesting Facts about 4-[4-(2-methoxyphenyl)piperazin-1-yl]-1-(3,4,5-trimethoxyphenyl)butan-1-ol; dihydrochloride

This intriguing chemical compound exhibits a unique blend of characteristics that make it particularly noteworthy in the field of medicinal chemistry. Here are some interesting aspects:

  • Pharmacological Interest: This compound is known for its potential as a psychoactive agent, and it has attracted attention for its possible implications in treating various neurological disorders.
  • Structural Complexity: Its structure features a piperazine ring, a common motif in many pharmaceutical compounds, which enhances the versatility of the molecule by allowing for varied interactions with biological targets.
  • Substituent Influence: The presence of multiple methoxy groups on the phenyl rings can significantly alter the physicochemical properties of the compound, affecting its lipophilicity and bioavailability.
  • Research Potential: Due to its complex architecture, this compound serves as an interesting subject for structure-activity relationship (SAR) studies, which may lead to the development of more effective derivatives.
  • Formulation Considerations: The dihydrochloride salt form of this compound may enhance its solubility and stability, making it more suitable for pharmaceutical applications.

Scientifically speaking, the exploration of this compound opens doors to a deeper understanding of drug design and development, marrying the intricate chemistry of synthetic routes with potential therapeutic benefits. As noted by researchers, “the subtle shifts in structural components can lead to profound changes in biological activity”, emphasizing the critical role of chemical structure in pharmacology.

In summary, 4-[4-(2-methoxyphenyl)piperazin-1-yl]-1-(3,4,5-trimethoxyphenyl)butan-1-ol; dihydrochloride stands as a compelling candidate for further investigation, highlighting the intricate connection between chemical properties and biological effects.

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