Haloperidol

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Identification

Molecular formula
C21H23ClFNO2
CAS Number
52-86-8
IUPAC Name
4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidyl]-1-(4-fluorophenyl)butan-1-one
Molecular Weight
375.86g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.1946g/cm3
Synonyms
haloperidol
Interesting facts

Interesting Facts about 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidyl]-1-(4-fluorophenyl)butan-1-one

This compound, often referred to in scientific literature due to its intriguing structure and potential applications, sits at the intersection of medicinal chemistry and pharmacology. Here are some interesting insights:

  • Pharmacological Relevance: The presence of both chlorophenyl and fluorophenyl groups suggests a potential for significant interactions with biological systems. These halogenated aromatic compounds often enhance binding affinity to biological targets.
  • Potential Therapeutic Uses: Compounds with a piperidine backbone are frequently explored for their roles as antidepressants, antipsychotics, and anxiolytics. This particular compound may offer insights into the development of new therapeutic agents.
  • Synthesis Challenges: The synthesis of compounds like this can be intricate, requiring multiple steps of functional group transformations. Such processes demand a deep understanding of organic reaction mechanisms and often the use of protecting groups.
  • Structure-Activity Relationship (SAR): Researchers often investigate how modifications to the structure affect biological activity. The interplay between the hydroxyl group and the various aromatic rings in this compound can yield critical data in SAR studies.
  • Emerging Research: Current studies may focus on the compound's effect on neurotransmitter systems and its potential implications for treating mood disorders, which underscores the importance of continued research in this area.

In conclusion, 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidyl]-1-(4-fluorophenyl)butan-1-one is a fascinating compound with numerous avenues for exploration from a chemical and medicinal perspective. As the field of medicinal chemistry progresses, compounds like this could lead to breakthrough developments in pharmacotherapy.

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