Chlorambucil
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- Molecular formula
- C14H19Cl2NO2
- CAS Number
- 305-03-3
- IUPAC Name
- 4-[4-[bis(2-chloroethyl)amino]phenyl]butanoic acid
- Molecular Weight
- 304.22g/mol
- Melting Point
- (Celsius)
- Boiling Point
- (Celsius)
- Density
- 1.1990g/cm3
- Synonyms
- chlorambucil
Identification
Interesting facts
Interesting Facts about 4-[4-[bis(2-chloroethyl)amino]phenyl]butanoic acid
This compound, often associated with medicinal chemistry, is noteworthy for its unique structure and potential pharmacological applications. Here are some intriguing aspects:
- Bioactive Potential: The compound is part of a class of compounds that serve as anticancer agents. Its design includes a bis(2-chloroethyl)amino moiety, which is known to be effective in targeting rapidly dividing cells.
- Synthetic Pathways: The synthesis of this compound typically involves multi-step reactions which may include alkylation and coupling reactions. This complexity showcases the beauty of organic synthesis and the creativity chemists employ when designing new molecules.
- Mechanism of Action: Like many anticancer drugs, it is believed to operate through the formation of cross-links in DNA. This disrupts the cancer cell's ability to replicate, ultimately leading to cell death. The ability to interfere with DNA dynamics makes compounds of this nature invaluable in chemotherapy regimes.
- Research Applications: Ongoing studies focus on understanding the complete pharmacodynamics and pharmacokinetics of this compound. Researchers are particularly interested in how functional groups on the molecule influence its therapeutic efficacy and side effect profile.
- Toxicology and Safety: With great potency comes the necessity for thorough toxicological evaluations. Researchers are continually investigating ways to minimize side effects while maximizing the therapeutic window of such potent compounds.
In summary, 4-[4-[bis(2-chloroethyl)amino]phenyl]butanoic acid embodies the intersection of chemistry and medicine, reminding us of the vast potentials held within organic compounds. As our understanding deepens, compounds like this may not only provide insight into innovative cancer treatments but also inspire the next generation of chemists in their quest for drug discovery.