Afatinib

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Identification

Molecular formula
C24H25ClFN5O3
CAS Number
439081-18-2
IUPAC Name
4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol
Molecular Weight
485.94g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.2396g/cm3
Appearance
Afatinib is a white to slightly yellowish powder. It is typically known for its pure white crystalline form.
Synonyms
JANEX-1
Interesting facts

Interesting Facts about 4-[(6,7-Dimethoxyquinazolin-4-yl)amino]phenol

This compound, known for its complex structure, is a prime example of the fascinating world of organic chemistry and its applications in medicinal chemistry. Here's what makes it noteworthy:

  • Diverse Applications: Compounds like 4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol are often explored for their potential therapeutic properties, particularly in the field of cancer research and as antibacterial agents.
  • Structure-Activity Relationship (SAR): The unique features of its molecular architecture allow scientists to investigate how modifications to the quinazoline or phenol moieties can influence biological activity, presenting a rich avenue for drug design.
  • Quinazoline Derivative: Quinazoline-based compounds are of great interest due to their involvement in various biological activities, including anti-inflammatory, anti-tumor, and anti-viral effects. This particular variant emphasizes how small changes in the chemical structure can lead to different biological outcomes.
  • Research Potential: Scientists are constantly in search of new compounds that can exhibit novel pharmacological effects. This compound’s unique combination of pharmacophores provides a solid foundation for further research and discovery.

"Science knows no borders; it acknowledges no race; it respects no religion; it values no nationality." – Louis Pasteur

The significance of compounds such as 4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol extends beyond their chemical complexity. They embody the intricate connection between chemistry and its impact on human health, showcasing how the manipulation of molecular structures can lead to groundbreaking innovations in treatment and therapy.

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