Zidovudine

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Identification

Molecular formula
C10H13N5O4
CAS Number
30516-87-1
IUPAC Name
4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one
Molecular Weight
267.24g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.5300g/cm3
Synonyms
cytidine
Interesting facts

Interesting Facts about 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one

This compound is a fascinating instance of the intersection between organic chemistry and medicinal applications. A member of the pyrimidine family, it features several bioactive characteristics that contribute to its function in pharmacology. Here are some engaging points about this intriguing compound:

  • Biological Role: The molecule plays a significant role in the synthesis of nucleotides, which are essential for RNA and DNA formation. This makes it pivotal in understanding cellular processes and genetic material.
  • Structural Complexity: The compound contains a unique tetrahydrofuran ring, known for its role in carbohydrate chemistry. This sugar-like structure is also responsible for many interactions within biological systems, impacting enzyme activities.
  • Potential Therapeutic Applications: Research has suggested its possible usage as an antiviral agent, particularly in the treatment of diseases caused by viral infections. The structural properties may enhance its affinity for viral targets.
  • Stereochemistry Matters: The compound showcases chirality, with specific configurations that could influence its bioactivity. The R and S designations refer to the orientation of atoms in space, a factor critical in pharmacodynamics.
  • Research Interest: Scientists are continuously exploring its derivatives to potentially enhance efficacy and reduce side effects. The ongoing studies highlight how small modifications in structure can lead to significant changes in behavior and activity.

In summary, 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one encapsulates both complexity and utility, making it a star compound in both organic synthesis and medicinal chemistry. As research evolves, its applications may expand further, offering new avenues for therapeutics.

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