Zidovudine

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Identification

Molecular formula
C10H13ClN5O4
CAS Number
30516-87-1
IUPAC Name
4-amino-1-[5-(chloromethyl)-3,4-dihydroxy-tetrahydrofuran-2-yl]pyrimidin-2-one
Molecular Weight
267.19g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.6800g/cm3
Synonyms
MLS003115947
Interesting facts

Interesting Facts about 4-amino-1-[5-(chloromethyl)-3,4-dihydroxy-tetrahydrofuran-2-yl]pyrimidin-2-one

The compound 4-amino-1-[5-(chloromethyl)-3,4-dihydroxy-tetrahydrofuran-2-yl]pyrimidin-2-one is a fascinating member of the pyrimidine family, known for its diverse applications in medicinal chemistry. Here are some compelling facets of this intriguing molecule:

  • Bioactivity: This compound exhibits potential antiviral and antibacterial properties. Its unique structure allows it to interact with biological targets, making it a candidate for further research in drug development.
  • Synthetic Pathways: Synthetic routes leading to this compound often involve multi-step reactions that can be insightful for chemistry students exploring the synthesis of heterocyclic compounds.
  • Structure-Activity Relationship: The presence of the chloromethyl and dihydroxy groups significantly influences its biological activity. Understanding how these modifications affect potency is essential in medicinal chemistry.
  • Research Potential: There is ongoing research into the derivatives of this compound, seeking to enhance its efficacy and reduce potential side effects. It’s a prime example of how small changes in chemical structure can yield significant variations in biological response.
  • Literature Reference: The exploration of similar compounds can be traced back in scientific literature, highlighting their relevance in drug discovery. References to related studies provide a rich backdrop for understanding the continuing interest in pyrimidine derivatives.

As a part of a larger class of pharmaceuticals, this compound underscores the synergy between structure and activity in drug design. With its diverse applications and ongoing investigational studies, 4-amino-1-[5-(chloromethyl)-3,4-dihydroxy-tetrahydrofuran-2-yl]pyrimidin-2-one serves as a notable example for both researchers and students in the field of chemistry.

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