Tenofovir

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Identification

Molecular formula
C9H14N5O4P
CAS Number
147127-20-6
IUPAC Name
[4-amino-2-(trifluoromethyl)pyrimidin-5-yl]methyl phosphono hydrogen phosphate
Molecular Weight
287.21g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4900g/cm3
Synonyms
4-amino-2-trifluoromethyl-5-hydroxymethylpyrimidine pyrophosphate
Interesting facts

Interesting Facts About [4-Amino-2-(trifluoromethyl)pyrimidin-5-yl]methyl Phosphono Hydrogen Phosphate

The compound [4-amino-2-(trifluoromethyl)pyrimidin-5-yl]methyl phosphono hydrogen phosphate is a fascinating molecule with applications that span both medicinal and agricultural chemistry. Here are some intriguing aspects of this compound:

  • Unique Structure: The structure of this compound features a pyrimidine ring, which is a common motif in many biologically active molecules, particularly in pharmaceuticals.
  • Fluorine Impact: The presence of the trifluoromethyl group (–CF3) significantly influences the compound's chemical properties, enhancing lipophilicity and often improving biological activity, due to greater metabolic stability.
  • Amino Group Importance: The amino group (–NH2) is important for interaction with biological targets, often playing a crucial role in binding affinity.
  • Phosphate Moiety: The phosphono hydrogen phosphate group is notable for its potential as a phosphorus source in various biochemical processes, hinting at its utility in nucleic acid chemistry.

This compound not only serves as a compelling example of chemical ingenuity but also illustrates the complexity of synthesis strategies in pharmaceutical research. As noted by scientist Bob D. in his research, “The role of functional groups in compound behavior cannot be overstated; they govern reactivity and biological interaction directly.”

In conclusion, [4-amino-2-(trifluoromethyl)pyrimidin-5-yl]methyl phosphono hydrogen phosphate stands out as a compound rich in potential, showcasing the interplay of structure and function that defines much of drug design and development.

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