Sulfamethizole

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Identification

Molecular formula
C9H10N4O2S
CAS Number
144-82-1
IUPAC Name
4-amino-N-(3,4-dimethylisoxazol-5-yl)benzenesulfonamide
Molecular Weight
270.33g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4460g/cm3
Synonyms
sulfisoxazole
Interesting facts

Interesting Facts about 4-amino-N-(3,4-dimethylisoxazol-5-yl)benzenesulfonamide

4-amino-N-(3,4-dimethylisoxazol-5-yl)benzenesulfonamide is a fascinating compound that showcases the complexity and versatility of sulfonamide derivatives. Here are some compelling insights into this intriguing chemical:

  • Pharmacological Significance: As a sulfonamide, this compound belongs to a well-known class of antibiotics. Sulfonamides have been instrumental in the treatment of bacterial infections, making them a crucial discovery in medicinal chemistry.
  • Mechanism of Action: This compound works primarily by inhibiting bacterial folate synthesis. By mimicking para-aminobenzoic acid (PABA), it disrupts the production of folate, which is essential for bacterial growth and reproduction.
  • Structural Diversity: The presence of the isoxazole ring in its structure introduces unique properties, enhancing the compound's interaction with biological targets. This makes it an interesting candidate for further development in pharmaceutical research.
  • Research Potential: Studies on sulfonamides and their derivatives continue to reveal new therapeutic potentials. This compound, with its specific structure, might contribute to the development of new drugs, particularly in overcoming antibiotic resistance.
  • Known Analogues: The chemical structure hints at a variety of possible derivatives, which can be synthesized and tested. This could potentially lead to a range of derivatives with varying biological activities.

In summary, the exploration of 4-amino-N-(3,4-dimethylisoxazol-5-yl)benzenesulfonamide exemplifies the rich tapestry of chemical research where structural modifications can vastly influence pharmacological outcomes. As we continue to understand its mechanisms and interactions, the potential for new medicinal applications remains an exciting frontier in chemistry.

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