4-(aminomethyl)benzenesulfonamide

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Identification

Molecular formula
C7H10N2O2S
CAS Number
33384-90-0
IUPAC Name
4-(aminomethyl)benzenesulfonamide
Molecular Weight
186.23g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4000g/cm3
Synonyms
mafenide
Interesting facts

Interesting Facts about 4-(Aminomethyl)benzenesulfonamide

4-(Aminomethyl)benzenesulfonamide, commonly known as AMS, is an intriguing compound that is widely used in medicinal chemistry and pharmaceuticals. Here are some fascinating insights:

  • Pharmaceutical Applications: AMS plays a crucial role in the synthesis of various pharmaceuticals, particularly as a component in drug development for treating infectious diseases.
  • Mechanism of Action: It is effective in inhibiting the enzyme dihydropteroate synthase, thus acting as a potential antibacterial agent. This makes it significant in combating microbial infections.
  • Sulfonamide Family: As a member of the sulfonamide group, AMS shares a unique trait with other compounds in this family, which is their sulfonamide functional group that contributes to their biological activity.
  • Research Utility: Beyond its clinical applications, AMS is often used in laboratory settings to study enzyme kinetics and mechanisms of action in biochemical research.
  • Structural Importance: The presence of both an amine and a sulfonamide group enhances its solubility and reactivity, making AMS an important target in drug design.

In summary, 4-(Aminomethyl)benzenesulfonamide is more than just a chemical compound; it is a vital player in the realm of medicinal chemistry, contributing significantly to the development of antibiotic therapies and providing rich opportunities for scientific exploration. As the field continues to evolve, compounds like AMS remain at the forefront of innovation in combatting bacterial resistance and enhancing therapeutic efficacy.

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