4-Chloro-2-(trifluoromethyl)benzimidazole

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Identification

Molecular formula
C8H4ClF3N2
CAS Number
138926-09-3
IUPAC Name
4-chloro-2-(trifluoromethyl)-1H-benzimidazole
Molecular Weight
222.58g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.5987g/cm3
Synonyms
2338-31-0
Interesting facts

Interesting Facts about 4-Chloro-2-(trifluoromethyl)-1H-benzimidazole

4-Chloro-2-(trifluoromethyl)-1H-benzimidazole is a fascinating compound that belongs to the class of benzimidazoles, which are known for their diverse biological activities. This compound, in particular, has several noteworthy properties and potential applications.

Key Characteristics

  • Biological Significance: Benzimidazole derivatives, including this compound, are often studied for their anti-parasitic, anti-cancer, and anti-inflammatory effects. They serve as crucial leads in the development of new therapeutic agents.
  • Fluorinated Moiety: The presence of the trifluoromethyl group enhances lipophilicity, which can improve the bioavailability and transport of the compound across biological membranes.
  • Chlorine Substitution: The 4-chloro group can influence the electronic properties and reactivity of the molecule, potentially affecting its interaction with target proteins in biological systems.

Applications

This compound's unique structure allows it to be potentially used in various fields such as:

  • Pharmaceutical Development: As mentioned, its derivatives can be pivotal in drug discovery, particularly for antimicrobial and antifungal agents.
  • Agricultural Science: Compounds with similar structures may serve as pesticides or herbicides, showcasing the versatility of benzimidazole derivatives.
  • Material Science: The properties of halogenated compounds often lend themselves to interesting interdisciplinary applications, such as in the development of advanced materials.

The study of 4-chloro-2-(trifluoromethyl)-1H-benzimidazole opens the door to a wealth of research opportunities and insight into the intricate world of organic synthesis and pharmacology. As Albert Einstein famously said, “The important thing is not to stop questioning. Curiosity has its own reason for existing.” Exploring compounds like this one embodies that spirit of inquiry, pushing the frontiers of science forward.

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