Lorazepam

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Identification

Molecular formula
C18H11ClN4O
CAS Number
846-49-1
IUPAC Name
(4-chlorophenyl)-[3-(2H-tetrazol-5-ylmethyl)indol-1-yl]methanone
Molecular Weight
321.77g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4670g/cm3
Synonyms
Intrazole
Interesting facts

Interesting Facts about (4-chlorophenyl)-[3-(2H-tetrazol-5-ylmethyl)indol-1-yl]methanone

This fascinating compound belongs to the family of indole derivatives, which are often noted for their rich structural diversity and broad biological activities. The presence of both a ketone functional group and a tetrazole moiety gives this compound a unique profile that piques the interest of chemists and pharmacologists alike.

Key Features

  • Diversity of Applications: Compounds containing indole structures are frequently investigated for their potential as therapeutics, including anti-cancer and anti-inflammatory agents.
  • Novel Functional Groups: The inclusion of the tetrazole ring, known for its stability and versatility in synthetic chemistry, may enhance the compound's biological activity and solubility.
  • Chlorine Substitution: The 4-chloro substitution on the phenyl ring can significantly influence the electronic properties and reactivity, making it a prime subject for structure-activity relationship (SAR) studies.

One of the most intriguing aspects of this compound is its potential interaction with biological targets. As noted by researchers, "The unique combination of indole and tetrazole frameworks is a promising avenue for developing novel pharmacological agents." This highlights the ongoing interest in exploring how such compounds can impact various biological processes.

Future Implications

The study of (4-chlorophenyl)-[3-(2H-tetrazol-5-ylmethyl)indol-1-yl]methanone opens up numerous avenues for future research:

  1. Investigating the antitumor potential through cell line assays.
  2. Exploring applications in neuropharmacology due to indole's known effects on neurotransmitter systems.
  3. Utilizing automated medicinal chemistry platforms for high-throughput screening.

This compound serves as a prime example of how structural modifications can lead to remarkable changes in biological activity, making it a valuable candidate for further study in medicinal chemistry.

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