4,6-Dichloro-2-(trifluoromethyl)-1H-benzimidazole

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Identification

Molecular formula
C8H3Cl2F3N2
CAS Number
51395-75-6
IUPAC Name
4,6-dichloro-2-(trifluoromethyl)-1H-benzimidazole
Molecular Weight
251.99g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.6391g/cm3
Synonyms
4228-88-0
Interesting facts

Interesting Facts about 4,6-Dichloro-2-(trifluoromethyl)-1H-benzimidazole

4,6-Dichloro-2-(trifluoromethyl)-1H-benzimidazole is a fascinating compound in the realm of organic chemistry, particularly known for its structural complexity and potential applications. Below are some intriguing aspects of this compound:

  • Structural Features: This compound is characterized by the presence of a benzimidazole core, which is a bicyclic structure consisting of a fused benzene and imidazole ring. The presence of both chlorine and a trifluoromethyl group at specific positions highlights the *diversity of functionalization* possible within this class of compounds.
  • Biological Activities: Compounds like 4,6-dichloro-2-(trifluoromethyl)-1H-benzimidazole have been studied for their *antimicrobial* and *antiparasitic* properties. Benzimidazoles are known to exhibit significant bioactivity, making them of interest in pharmaceutical research.
  • Fluorine's Role: The trifluoromethyl group, a common motif in drug design, can enhance *lipophilicity* and *bioavailability*. The introduction of fluorine atoms can also alter the acidity, reactivity, and overall metabolism of the compound, providing an opportunity for innovative therapeutic strategies.
  • Applications in Agriculture: Due to their efficacy, benzimidazole derivatives are utilized in agriculture as fungicides and herbicides, contributing to crop protection and yield enhancement. Such compounds are pivotal in ensuring food security.
  • Research Potential: The unique set of functional groups in this compound creates a platform for further modification and exploration. Researchers continue to investigate its potential for developing new materials, catalysts, and therapeutic agents.

In summary, 4,6-dichloro-2-(trifluoromethyl)-1H-benzimidazole exemplifies the importance of structural diversity in medicinal chemistry and agricultural sciences. The ongoing exploration of its properties can lead to the development of innovative solutions in various fields.

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