Remdesivir

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Identification

Molecular formula
C27H35N6O8P
CAS Number
1809249-37-3
IUPAC Name
(4aR,6R,7R,7aS)-6-(6-amino-8-bromo-purin-9-yl)-2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol
Molecular Weight
602.59g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
2.0000g/cm3
Synonyms
8-bromo-cAMP
Interesting facts

Interesting Facts about (4aR,6R,7R,7aS)-6-(6-amino-8-bromo-purin-9-yl)-2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol

This intriguing compound belongs to a class of molecules known for their unique structural features and biological activity. Here are some interesting aspects that highlight its significance:

  • Complex Structure: The compound showcases a sophisticated arrangement of multiple rings and functional groups, including a purine base and a dioxaphosphinin system. This complex architecture allows for unique interactions with biological systems.
  • Potential Bioactivity: Due to the presence of the purine moiety, this compound has potential applications in pharmacology, particularly in the fields of nucleic acid research and drug development. Compounds of this nature can be integral in designing antiviral or anticancer therapies.
  • Bridging Chemistry and Biology: The diverse functionalities within its structure exemplify the interplay between organic chemistry and biological functions, revealing a prime candidate for studies in medicinal chemistry.
  • Stereochemistry Matters: The stereochemical configuration of this compound, indicated by the (4aR,6R,7R,7aS) notation, is crucial. It influences the compound's reactivity and the biological recognition by target enzymes or receptors.
  • Applications in Drug Design: The modifications on the purine nucleus, including amino and bromo substituents, can significantly alter the pharmacokinetic properties, leading to variations in potency, selectivity, and side effects.
  • Research Interest: Due to its complexity and potential biological relevance, this compound is likely to be of great interest in research circles, leading to potential further studies to unravel all its biochemical roles.

Overall, (4aR,6R,7R,7aS)-6-(6-amino-8-bromo-purin-9-yl)-2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol is a remarkable compound that exemplifies the intricate relationship between structure and function in chemical compounds, especially those with biological significance.

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