Galanthamine hydrochloride

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Identification

Molecular formula
C17H21NO3·HCl·H2O
CAS Number
1953-04-4
IUPAC Name
(4S,4aR,7aR,12bS)-9-methoxy-3-methyl-1,2,4,4a,5,6,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one;hydrate;hydrochloride
Molecular Weight
368.89g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.3200g/cm3
Interesting facts

Interesting Facts about (4S,4aR,7aR,12bS)-9-Methoxy-3-methyl-1,2,4,4a,5,6,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one;hydrate;hydrochloride

This intriguing compound, belonging to the class of isoquinoline derivatives, offers a wealth of scientific interest due to its unique structure and potential biological activities. Here are some engaging insights:

  • Structural Complexity: The compound showcases a remarkable multi-ring structure that is characteristic of many natural products, suggesting intricate biosynthetic pathways.
  • Biological Significance: Research has indicated that isoquinoline derivatives often possess notable pharmacological properties. They can exhibit pharmacological effects such as antitumor, antimicrobial, and anti-inflammatory activities.
  • Hydrochloride Form: The hydrochloride salt form of this compound enhances its solubility, thereby facilitating its use in various applications, particularly in therapeutic settings.
  • Stereochemistry: The specific stereochemistry represented by the various stereocenters (S and R configurations) in the molecular structure underscores the importance of chirality in biological activity, influencing how the compound interacts with biological systems.
  • Natural Origins: Similar compounds are often found in nature, frequently derived from plants, opening avenues for exploration in herbal medicine and natural product chemistry.
  • Research Applications: Given its structural features, this compound could serve as a lead structure in drug design, prompting further studies to elucidate its mechanism of action and explore its therapeutic potential.

In conclusion, the fascinating chemistry of (4S,4aR,7aR,12bS)-9-methoxy-3-methyl-1,2,4,4a,5,6,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one;hydrate;hydrochloride exemplifies the intersection of structural elegance and biological relevance, making it a worthy subject of study in the field of medicinal chemistry.

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