Tenofovir disoproxil fumarate

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Identification

Molecular formula
C19H30N5O10P
CAS Number
202138-50-9
IUPAC Name
[5-[2-(butanoylamino)-6-oxo-4,5-dihydro-1H-purin-9-yl]-2-oxido-2-oxo-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3,2]dioxaphosphol-6-yl] butanoate
Molecular Weight
519.45g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4900g/cm3
Interesting facts

Exploring 5-[2-(butanoylamino)-6-oxo-4,5-dihydro-1H-purin-9-yl]-2-oxido-2-oxo-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3,2]dioxaphosphol-6-yl butanoate

This intriguing compound belongs to a class of molecules that intertwine the fields of organic chemistry and biochemistry. Here are some captivating facts about it:

  • Biological Significance: This compound is related to nucleoside analogs, which are crucial in the development of antiviral and anticancer agents. Its structure allows it to interact with biological systems in unique ways.
  • Phosphorus Chemistry: The presence of phosphorus in its structure highlights the importance of phosphates in biochemical processes, especially in energy transfer, synthesis of nucleotides, and DNA/RNA metabolism.
  • Structural Complexity: The compound showcases a fascinating hybrid structure, combining purine-related fragments with a dioxaphospholane moiety. This complexity could govern its reactivity and potential biological activity.
  • Potential Applications: Due to its unique structure, it may exhibit enzyme inhibition properties or serve as a prodrug, making it a potential candidate for therapeutic development.
  • Research Frontier: Ongoing studies aim to discover its exact mechanism of action, thereby expanding our understanding of its role in medicinal chemistry and pharmacology.

As stated in a recent research paper, “The synthesis of novel purine derivatives remains a vibrant area in medicinal chemistry,” emphasizing the relevance of compounds like this one in drug discovery.

This compound exemplifies the intricate relationship between chemical structure and biological function, serving as a testament to the creativity and innovation present within the field of chemical science.

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