Tenofovir

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Identification

Molecular formula
C9H14N5O4P
CAS Number
147127-20-6
IUPAC Name
5-[2,4-dioxo-6-(2,3,4,5-tetrahydroxypentylamino)-1H-pyrimidin-5-yl]pentylphosphonic acid
Molecular Weight
287.22g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.5000g/cm3
Synonyms
PD039789
Interesting facts

Exploring 5-[2,4-dioxo-6-(2,3,4,5-tetrahydroxypentylamino)-1H-pyrimidin-5-yl]pentylphosphonic acid

This compound, a fascinating member of the phosphonic acid family, presents a unique structure that provides numerous avenues for scientific exploration. It’s notable for its application in medicinal chemistry and agricultural science, largely due to its ability to act as a phosphonate, which can mimic naturally occurring phosphate-containing compounds.

Unique Characteristics

  • Pharmacological Potential: The presence of a pyrimidine ring grants this compound potential as a drug candidate, particularly in the realms of antiviral and anticancer therapies.
  • Hydroxypentyl Chain: The tetrahydroxypentylamino group showcases impressive potential for forming strong interactions with biological targets, which could enhance its effectiveness in therapeutic applications.
  • Phosphonic Acid Group: This group is instrumental in mimicking phosphate groups, thus may influence cellular processes and signaling pathways.

Moreover, compounds of this nature are actively researched for their role in various biological processes. As a chemist, it is fascinating to explore how slight modifications in the molecular structure can lead to vastly different biological activities. In the context of drug development, understanding the structure-activity relationship (SAR) of this compound can provide insights into designing more effective medications.

Quote to Reflect Upon

As noted by renowned chemists, "The beauty of chemistry is in its intricacies; a single atom's rearrangement can lead to revolutionary transformations." This compound embodies that idea, illustrating how specific structural features yield unique properties and potentials.

In conclusion, 5-[2,4-dioxo-6-(2,3,4,5-tetrahydroxypentylamino)-1H-pyrimidin-5-yl]pentylphosphonic acid serves as an excellent example of the diverse and complex nature of chemical compounds. Its applications, especially in pharmaceuticals, make it a compound worth studying and understanding in depth.

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