Zidovudine

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Identification

Molecular formula
C10H13N5O4P
CAS Number
30516-87-1
IUPAC Name
[5-(4-amino-5-methyl-2-oxo-pyrimidin-1-yl)-3-hydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate
Molecular Weight
267.24g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.5600g/cm3
Synonyms
{[(2R, 3S, 5R)-5-(4-amino-5-methyl-2-oxo-1, 2-dihydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}phosphonic acid
Interesting facts

Interesting Facts about [5-(4-amino-5-methyl-2-oxo-pyrimidin-1-yl)-3-hydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate

This fascinating compound presents a rich assortment of features that make it noteworthy in the realm of chemistry, particularly in medicinal chemistry and pharmacology. Here are some intriguing facts:

  • Pharmaceutical Highlights: This compound is derived from the classical framework of pyrimidine—an essential structure in many pharmaceuticals. Its modifications promote various biological activities, making it valuable in drug design.
  • Dual Role: Not only does it contain a pyrimidine component, but it also integrates a tetrahydrofuran ring. This unique combination may enhance its pharmacological properties, contributing to its bioactivity and stability.
  • Functional Groups: The compound features multiple functional groups, including:
    • Amino group (NH2) which is key for biological interactions
    • Hydroxyl group (OH), enhancing solubility and reactivity
    • Dihydrogen phosphate, a common moiety that can affect cellular mechanisms
  • Research Applications: Scientists are exploring this compound's potential in therapeutic interventions, particularly for disorders related to nucleic acid metabolism given the presence of the pyrimidine base.
  • Quote to Remember: As noted in the field of medicinal chemistry, “The intricacies of molecular design can lead to breakthroughs in treatments and technologies; every atom counts.”

Understanding compounds like this one is paramount for chemists and pharmacologists as they explore innovative solutions for complex health challenges. Its comprehensive structure invites ongoing research and discovery, potentially paving the way for novel therapeutic agents.

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