Pyrimethamine

ADVERTISEMENT

Identification

Molecular formula
C12H13ClN4
CAS Number
58-14-0
IUPAC Name
5-(4-chlorophenyl)-6-ethyl-pyrimidine-2,4-diamine
Molecular Weight
248.72g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.3100g/cm3
Synonyms
pyrimethamine
Interesting facts

Interesting Facts About 5-(4-Chlorophenyl)-6-ethyl-pyrimidine-2,4-diamine

5-(4-Chlorophenyl)-6-ethyl-pyrimidine-2,4-diamine is a fascinating compound that captures the attention of both chemists and pharmacologists due to its structure and potential applications. Here are some insightful details:

  • Pyrimidine Framework: The compound contains a pyrimidine ring, which is a key feature in many biological molecules, including nucleic acids. This structure contributes to its biological activity.
  • Chlorophenyl Substituent: The presence of a 4-chlorophenyl group can significantly influence the compound's properties, including its lipophilicity and binding affinities to various biological targets.
  • Pharmacological Potential: Compounds like this one are often investigated for their role as potential therapeutic agents. They could serve as inhibitors in various pathways, making them interesting candidates for drug development.
  • Structure-Activity Relationship (SAR): Researchers focus on this aspect to understand how modifications to the compound's structure can enhance its efficacy or reduce side effects, revealing the compound's versatility.
  • Synthetic Challenges: The synthesis of such complex structures often involves multiple steps which can pose challenges in terms of yield and purity, making them a topic of research in synthetic organic chemistry.

Overall, 5-(4-chlorophenyl)-6-ethyl-pyrimidine-2,4-diamine stands as an intriguing member of the pyrimidine family, bridging the gap between structure and function in medicinal chemistry. Its unique features continue to fuel research into its potential applications in health sciences.

ADVERTISEMENT