Tenofovir disoproxil fumarate

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Identification

Molecular formula
C19H30N5O10P
CAS Number
147127-20-6
IUPAC Name
[[5-(6-amino-2-chloro-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate
Molecular Weight
635.51g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.6940g/cm3
Synonyms
PD025689
Interesting facts

Exploring [5-(6-amino-2-chloro-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate

This compound is quite a fascinating example of biomolecules that bridge organic chemistry with biochemistry. Its complex structure highlights a myriad of functional groups and contributes to its unique properties and potential applications. Here are some intriguing facts:

  • Biological Significance: This compound represents a category of nucleotides that play an essential role in cellular processes, particularly in nucleic acid metabolism.
  • Pharmacological Potential: With elements derived from purine metabolism, it poses interesting possibilities as a pharmaceutical agent. Its structure suggests potential interactions with various biological targets, particularly in the realm of anti-cancer therapies.
  • Chiral Centers: The presence of multiple chiral centers indicates that stereochemistry is crucial for its biological activity. This aspect is vital for chemists in drug design, as even slight alterations in stereo or geometric configuration can lead to significant changes in efficacy and safety.
  • Functional Diversity: The diverse functional groups present, such as amino and hydroxyl groups, give rise to a wide range of reactivity and interaction with biomolecules such as enzymes and receptors.
  • Research Applications: Due to its complex nature, this compound serves as a valuable tool in molecular biology studies, particularly in understanding mechanisms of action of other bioactive compounds.

Overall, the [5-(6-amino-2-chloro-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate is an example of how intricate chemical structures can provide vital clues to biological processes and therapeutic development. As highlighted by the famous saying in chemistry, "If you can’t explain it to a six-year-old, you don’t understand it yourself." This compound serves as an opportunity for both students and scientists to deepen their understanding of chemical intricacies and biological functions.

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