Tenofovir

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Identification

Molecular formula
C9H14N5O4P
CAS Number
147127-20-6
IUPAC Name
[5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-methyl-phosphinic acid
Molecular Weight
287.21g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4975g/cm3
Synonyms
9-{5-o-[hydroxy(methyl)phosphoryl]pentofuranosyl}-9h-purin-6-amine
Interesting facts

Interesting Facts about [5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-methyl-phosphinic acid

This fascinating compound, often categorized within the realm of nucleoside analogs, highlights the intricate interplay between organic chemistry and biological functions. Here are some engaging points about this compound:

  • Nucleoside Analog: It is structurally related to nucleosides, which are crucial for nucleic acid synthesis, and hence holds particular interest in medicinal chemistry for its potential therapeutic applications.
  • Potential in Antiviral Therapy: Compounds like this are often investigated for their antiviral properties. The ability to mimic the structure of natural nucleosides can lead to the inhibition of viral replication.
  • Structure-Activity Relationship (SAR): The unique combination of a purine base along with a sugar derivative and a phosphinic acid moiety offers a rich avenue for exploring how variations in structure can affect biological activity, making it a subject of interest for drug design.
  • Phosphinic Acids: This compound falls into the category of phosphinic acids, which are known for their capacity to act as potent inhibitors in biochemical pathways, specifically being studied for their use in target-specific therapies.
  • Research and Development: Ongoing research explores the effectiveness of this compound in treating various diseases, especially viral infections, making it a candidate for further development in pharmacology.

The intricacies of [5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-methyl-phosphinic acid lie not only in its chemical composition but also in its potential applications. As research progresses, scientists continue to unveil the depths of its function, emphasizing the ever-evolving connection between chemistry and therapy.

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