Tenofovir

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Identification

Molecular formula
C9H12N5O3P
CAS Number
147127-20-6
IUPAC Name
5-(6-aminopurin-9-yl)-N-cyclopropyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Molecular Weight
287.21g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4900g/cm3
Synonyms
5'-(N-Cyclopropyl)carboxamidoadenosine
Interesting facts

Interesting Facts about 5-(6-aminopurin-9-yl)-N-cyclopropyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide

This fascinating compound, often referred to as an analog of purine nucleosides, exhibits significant biological implications, particularly in the realm of medicinal chemistry. Its structural complexity and unique functional groups make it a compelling subject for research and study.

Biological Importance

  • Purine Analogs: The compound is an analog of essential nucleobases, which play a critical role in the composition of DNA and RNA. This similarity offers potential in understanding genetic mechanisms.
  • Potential Therapeutic Applications: Investigations into its pharmacological properties reveal potential applications in treating viral infections and cancers, where modulation of nucleic acid synthesis is crucial.
  • Enzyme Interaction: The compound may interact with specific enzymes, possibly acting as an inhibitor. This interaction could pave the way for novel therapeutic strategies designed to combat diseases.

Chemical Features

  • Cyclopropyl Group: The presence of the cyclopropyl moiety contributes to the compound's rigidity, which may enhance binding affinity to biological targets.
  • Hydroxyl Groups: The two hydroxyl groups introduce additional sites for hydrogen bonding, which may improve the compound's solubility and bioavailability.
  • Amino Group: The amino functional group may enhance the compound’s interaction with molecular receptors, offering insights into its potential as a drug candidate.

As researchers continue to explore the nuances of this compound, it stands as a testament to the intricate relationship between structure and function in medicinal chemistry. In the words of a leading chemist, "Understanding the details of these compounds can unlock new paths for innovation in therapy."

This compound exemplifies the exciting frontier of chemical research where molecular design strives to inform and enhance human health.

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