Fluorochloridol

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Identification

Molecular formula
C20H14Cl2FNO2
CAS Number
188416-29-7
IUPAC Name
5-chloro-3-(4-chlorophenyl)-N-(4-fluoro-2-methyl-phenyl)-2-hydroxy-benzamide
Molecular Weight
406.77g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.3800g/cm3
Synonyms
24283-57-6
Interesting facts

Interesting Facts about 5-Chloro-3-(4-chlorophenyl)-N-(4-fluoro-2-methyl-phenyl)-2-hydroxy-benzamide

This compound is a remarkable example of the intricate world of organic chemistry, particularly in the realm of medicinal chemistry and drug design. Here are some intriguing aspects:

  • Structural Complexity: The compound features a complex molecular structure with multiple functional groups, including chloro, fluoro, hydroxy, and amide groups. This diversity contributes to its unique properties and potential biological activity.
  • Pharmaceutical Relevance: Compounds like this one are often investigated for their potential therapeutic applications, particularly in fields such as oncology and neurology. The substitution patterns can affect interactions with biological targets.
  • Fluorine's Influence: The presence of fluorine atoms in organic compounds can enhance metabolic stability, oral bioavailability, and lipophilicity. This compound illustrates how strategic fluorination can lead to improved pharmacokinetic profiles.
  • Halogenation: The incorporation of chlorine and fluorine atoms can significantly alter the electronic properties of the aromatic system, potentially leading to increased potency or selectivity in biological interactions.
  • Hydrogen Bonding: The hydroxyl group in this compound opens avenues for hydrogen bonding interactions, which can be critical for binding affinity to enzyme active sites or receptor sites in biological systems.
  • Ligand Design: The intricate design of this compound reflects important concepts in ligand-based drug design, emphasizing how modifications in structure can lead to vastly different biological outcomes.

As you delve deeper into the study of compounds like 5-chloro-3-(4-chlorophenyl)-N-(4-fluoro-2-methyl-phenyl)-2-hydroxy-benzamide, remember that chemistry is as much about the **structure** and **functionality** as it is about the **application** in real-world scenarios. Each compound tells a story of how molecular features can influence broader outcomes in pharmacology and therapeutic efficacy.

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